発表論文

英文原著 Tabata, K., Arimoto, M., Arakawa, M., Nara, A., Saito, K., Omori, H., Arai, A., Ishikawa, T., Konishi, E., Suzuki, R., Matsuura, Y., Morita, E. Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum. Cell Rep. 2016 in press

Hao, F., Itoh, T., Morita, E., Shirahama-Noda, K., Yoshimori, T., Noda, T. The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity. FEBS Lett. 2016 590(1):161-173.

Suzuki, H., Tabata, K., Morita, E., Kawasaki, M., Kato, R., Dobson, RJ., Yoshimori, T., Wakatsuki, S. Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism. Structure. 2014 22(1):47-58.

Fujita, N.†, Morita, E. †, Itoh, T., Tanaka, A., Nakaoka, M., Osada, Y., Umemoto, T., Saitoh, T., Nakatogawa, H., Kobayashi, S., Haraguchi, T., Guan, J.L., Iwai, K., Tokunaga, F., Saito, K., Ishibashi, K., Akira, S., Fukuda, M., Noda, T., Yoshimori, T. Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin. J Cell Biol. 2013 203(1):115-28 †These authors contributed equally

Tripathi, L.P., Kambara, H., Chen, Y.A., Nishimura, Y., Moriishi, K., Okamoto, T., Morita, E., Abe, T., Mori, Y., Matsuura, Y., Mizuguchi, K. Understanding the biological context of NS5A-host interactions in HCV infection: a network-based approach. J Proteome Res. 2013 Jun 7;12(6):2537-51.

Katoh, H., Okamoto, T., Fukuhara, T., Kambara, H., Morita, E., Mori, Y., Kamitani, W., Matsuura, Y. Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation. J Virol. 2013 Jan;87(1):489-502.

Morita, E., Arii J, Christensen D, Votteler J, Sundquist WI. Attenuated protein expression vectors for use in siRNA rescue experiments. Biotechniques. 2012 Aug;0(0):1-5.

Tripathi LP, Kambara H, Moriishi K, Morita E, Abe T, Mori Y, Chen YA, Matsuura Y, Mizuguchi K. Proteomic analysis of hepatitis C virus (HCV) core protein transfection and host regulator PA28γ knockout in HCV pathogenesis: a network-based study. J Proteome Res. 2012 Jul 6;11(7):3664-79.

Fukuhara T, Kambara H, Shiokawa M, Ono C, Katoh H,Morita, E., Okuzaki D, Maehara Y, Koike K, Matsuura Y. Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus. J Virol. 22012 Aug;86(15):7918-33.

Morita, E., Yoshimori, T. Membrane recruitment of LC3 proteins during autophagosome formation. Hepatol Res. 2012 May;42(5):435-41.

Morita, E. ESCRT Connections: Factor Requirements for Multivesicular Body Formation, Virus Budding and Cell Division. FEBS J. 2012 Apr;279(8):1399-406

Katoh, H., Mori, Y., Kambara, H., Abe, T., Fukuhara, T., Morita, E., Moriishi, K., Kamitani, W., Matsuura, Y. Heterogeneous nuclear ribonucleoprotein A2 participates in the replication of Japanese encephalitis virus through an interaction with viral proteins and RNA. J Virol. 2011 85(21):10976-88

Morita, E., Sandrin, V., McCullough, J., Katsuyama, A., Hamilton, IB., Sundquist, WI. ESCRT-III protein requirements for HIV-1 budding. Cell Host Microbe. 2011, 3:235-42.

Matsunaga, K., Morita, E., Saitoh, T., Akira, S., Ktistakis, NT., Izumi, T., Noda, T., Yoshimori, T. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. J Cell Biol. 2010 190(4):511-21.

Morita, E., Colf, LA., Karren, MA., Sandrin, V., Rodesch, CK., Sundquist, WI. Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance. Proc Natl Acad Sci U S A. 2010 107(29):12889-94.

Bajorek, M., Morita, E., Skalicky, JJ, Morham, SG., Babst, M., Sundquist, WI. Biochemical analyses of human IST1 and its function in cytokinesis. Mol Biol Cell 2009 20(5):1360-73.

Kieffer, C., Skalicky JJ., Morita, E., De Domenico, I., Ward, DM., Kaplan, J., Sundquist, WI. A New Functionally Important ESCRT-III Recognition Mode for the VPS4 ATPases. Dev. Cell 2008, 15(1):62-73.

Chung, HY., Morita, E., von Schwedler, U., Müller, B., Kräusslich, HG. and Sundquist, WI.. NEDD4L Overexpression Rescues Release and Infectivity of HIV-1 Constructs Lacking PTAP and YPXL Late Domains. J Virol. 2008, 82(10):4884-97.

Morita, E., Sandrin, V., Chung, HY., Morham, SG., Gygi, SP., Rodesch, CK. and Sundquist,, WI. Human ESCRT and ALIX Proteins Interact with Proteins of the Midbody and Function in Cytokinesis. EMBO J, 2007, 26(19):4215-27.

Morita, E., Sandrin, V., Alam, SL., Eckert, DM., Gygi, SP., Sundquist, WI. Identification of MVB12 Proteins as Human ESCRT-I Subunits that Function in HIV Budding. Cell Host Microbe 2007, 2(1):19-28

Morita, E., Sundquist, WI. Retrovirus budding. Annu Rev Cell Dev Biol. 2004 20:395-425.

Nakashima, A., Morita, E., Saito, S., Sugamura, K. Human Parvovirus B19 nonstructural protein transactivates the p21/WAF1 through Sp1. Virology 2004 329:493-504.

von Schwedler, UK., Stuchell, M., Muller, B., Ward, DM., Chung, HY., Morita, E., Wang, HE., Davis, T., He, GP., Cimbora, DM., Scott, A., Krausslich, HG., Kaplan, J., Morham, SG., Sundquist, WI. The protein network of HIV budding. Cell. 2003 114:701-13.

Kanazawa, C., Morita, E., Yamada, M., Ishii, N., Miura, S., Asao, H., Yoshimori, T., Sugamura, K. Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation. Biochem Biophys Res Commun. 2003 309:848-56.

Morita, E., Nakashima, A., Asao, H., Sato, H., Sugamura, K. Human parvovirus B19 nonstructural protein (NS1) induces cell cycle arrest at G(1) phase. J Virol. 2003 77:2915-21.

Morita, E., Sugamura, K. Human parvovirus B19-induced cell cycle arrest and apoptosis. Springer Semin Immunopathol 2002 24:187-199.

Chisaka, H., Morita, E., Murata, K., Ishii, N., Yaegashi, N., Sugamura, K. A transgenic mouse model for nonimmune hydrops fetalis induced by the NS1 gene of human parvovirus B19. J Gen Virol. 2002 83:273-81.

Morita, E., Tada, K., Chisaka, H., Asao, H., Sato, H., Yaegashi, N., Sugamura, K. Human parvovirus B19 induces cell cycle arrest at G(2) phase with accumulation of mitotic cyclins. J Virol. 2001 75:7555-63.

Kasai, H., Morita, E., Hatakeyama, K., Sugiyama K. Characterization of haemagglutinin -esterase protein (HE) of murine corona virus DVIM by monoclonal antibodies. Arch Virol. 1998;143:1941-8.

Morita, E., Ebina, H., Muto, A., Himeno, H., Hatakeyama, K., Sugiyama, K. Primary structures of hemagglutinin-esterase and spike glycoproteins of murine coronavirus DVIM. Virus Genes 1998;17:123-8.
和文総説 田端桂介森田英嗣 ウイルス感染とオートファジー 臨床免疫・アレルギー科 2016 印刷中

森田英嗣 Multivesicular Bodyの形成とESCRT複合体の役割 生体の科学 2012 65:522-525

森田英嗣 エンベロープウイルスの出芽と細胞質分裂 生化学 2010 82:415-419

森田英嗣 エンベロープウイルス粒子形成の分子メカニズム 蛋白質 核酸 酵素 増刊号「メンブレントラフィックの奔流」.蛋白質 核酸 酵素 2008 53:2245-2250.

八重樫伸生、千坂泰、森田英嗣、多田孝太郎、岡村州博、菅村和夫 パルボウイルスB19の母子感染 ウイルス 2001 51:51-56

招待講演等 森田 英嗣 名古屋大学セミナー 招待講演、 2016.9 フラビウイルス増殖に関与する宿主因子の同定と機能解析


森田 英嗣 北海道大学獣医学部セミナー 招待講演、 2016.6 フラビウイルス増殖に関与する宿主因子の同定と機能解析


Morita, E.,The 65th Annual Meeting of the Japan Society for Cell Biology. Invited Lecture. 2013.6 Nagoya. Involvement of ESCRT Factors in Flavivirus Replication.


森田 英嗣 第10回ウイルスキャンプ 教育講演 2013.5 ESCRT経路を介したRNAエンベロープウイルス粒子形成の分子メカニズム


森田 英嗣 第19回トガ・フラビ・ペスチウイルス研究会 特別講演 2012.11 ESCRT経路を介したRNAエンベロープウイルス粒子形成の分子機構3. 森田 英嗣 第19回トガ・フラビ・ペスチウイルス研究会 特別講演 2012.11 ESCRT経路を介したRNAエンベロープウイルス粒子形成の分子機構


Morita, E., Invited Lecture. Institute for Tropical Medicine. Nagasaki University., 2012.7 Mechanisms of enveloped RNA virus budding and cytokinesis.


森田 英嗣 京都大学ウイルス研究所セミナー 招待講演、京都大学 2012.6 ESCRT経路を介したRNAエンベロープウイルス粒子形成の分子メカニズム


森田 英嗣 大阪大学微生物病研究所セミナー 招待講演、大阪大学2010.10 Multivesicular body とオートファゴソーム膜形成の分子メカニズム


Morita, E.,, 11th KUMAMOTO AIDS Seminar, Invited Lecture, Kumamoto Oct 2010, Identification of the ESCRT-III proteins required for HIV budding


Morita, E.,, Kobe University Global COE Program on Integrative Membrane Biology 4th Workshop, Invited Lecture, July 2010 Awaji, Identification of the ESCRT-III proteins required for retrovirus budding and cell division


Morita, E.,, International Symposium on Organelle Network: Microbiology, Immunology, and Cell Biology, Invited Lecture, July 2010, Identification of the ESCRT-III proteins required for retrovirus budding and cell division


森田 英嗣 第57回日本ウイルス学会学術集会ワークショップ口頭発表、東京2010.10レトロウイルスの出芽に必要なESCRT-IIIの同定


森田 英嗣 弘前大学遺伝子実験施設セミナー 招待講演、弘前大学2009. 7. HIV Budding and Cell Division


Morita, E.,, Sandrin, V., Sundquist, WI. Identification of the ESCRT-III Proteins Required for Retrovirus Budding. Cold Spring Harbor Laboratory Meeting, Retrovirus, New York, USA (May 2009) *oral presentation


森田 英嗣 BMB2008シンポジウム口頭発表 神戸2008.12 細胞質分裂におけるESCRT経路の役割


Morita, E., Tokyo Institute of Technology, Invited Lecture. Dec. 2008. HIV Budding and Cell Division


森田 英嗣 東京大学医科学研究所学友会セミナー 招待講演 東京大学2008.12 HIV-1粒子出芽と細胞分裂


森田 英嗣 国立感染症研究所 招待講演 東京大学2008.12 HIV-1粒子出芽と細胞分裂


森田 英嗣 東北大学大学院医学系研究科セミナー 招待講演 東北大学2008.7 ESCRT-I結合分子の同定とHIV-1粒子出芽における役割


森田 英嗣 大阪大学微生物病研究所セミナー 招待講演 大阪大学2008.7 ESCRT-I結合分子の同定とHIV-1粒子出芽における役割


Morita, E., Sandrin, V., Karren, MA., Gygi, SP., Morham, SG., Sundquist. WI. Identification of ESCRT-I Binding Factors Required for Efficient HIV-1 Release. Keystone Symposia, HIV Pathogenesis, 275, Banff, Canada, March 2008 *oral presentation


Morita, E.,Sandrin, V., Karren, MA., Gygi, SP., Morham, SG., Sundquist, WI. Identification of ESCRT-I Binding Factors Required for Efficient HIV-1 Release. 15th Conference on Retroviruses and Opportunistic Infection, 102, Boston, USA, February 2008 *oral presentation