Hayato Maeda

  • Title Associate Professor
  • Department Applied Biology and Food Sciences
  • Course Food Science Course
  • Research Field Food Chemistry
  • E-mail hayatosp [at]
    please substitute @ for [at]
  • Phone +81-172-39-3790


Food contains various components. They are important for our healthy life. In this laboratory, we are studying functional ingredients included in agricultural and fishery food products. For example, phytochemical and poly unsaturated fatty acids are useful for preventing life style-related diseases such as obesity, diabetes, and dyslipidemia. We are screening for these materials from food products.

 Evaluation methods are in vitro and in vivo studies. We usually use adipocytes cells, macrophage cells, hepatic cells etc. The active food components clarify by animal experiment. We also analyze functional ingredients contained in foods using high performance liquid chromatography (HPLC) and gas chromatography (GC).

Research Theme

Food science, Molecular nutrition, Lipid nutrition


Academic Society Affiliations

  1. Japan society for bioscience, biotechnology, and agrochemistry
  2. Japan oil chemists’ society
  3. Japanese society of nutrition and food science
  4. The Japanese Society of Fisheries Science 
  5. The japanese society for food science and technology
  6. Japanese society for food factors
  7. Japanese society for carotenoid research

Education & Appointments

1999-04 to  2003-03 Hokkaido University: Hakodate, Japan,
Bachelor(Faculty of Fisheries Sciences)

2003-04 to  2005-03 Hokkaido University: Hakodate, Japan,
Master’s degree(Graduate School of Fisheries Sciences)

2005-04 to  2008-03 Hokkaido University: Hakodate, Japan,
Doctor(Graduate School of Fisheries Sciences)

2008-04 to  2016-10 Hirosaki University: Hirosaki, Aomori, Japan
Assistant Professor(Faculty of agriculture and life science )

2016-11 to present Hirosaki University: Hirosaki, Aomori, Japan
Associate professor(Faculty of agriculture and life science)


・Academic research staff, Hirosaki University


Maeda H, Kanno S., Kodate M., Hosokawa M., Miyashita K. Fucoxanthinol, metabolite of fucoxanthin, improves obesity-induced inflammation in adipocyte cells. Marine drugs. 13, 4799-4813. (2015). 

Maeda H, Hosomi R., Koizumi M, Toda Y, Mitsui M, Fukunaga, K. Dietary cod protein decreases triacylglycerol accumulation and fatty acid desaturase indices in the liver of obese type-2 diabetic KK-Ay mice. Journal of Functional Foods. 14, 87-94. (2015). 

Maeda H. Nutraceutical effects of fucoxanthin for obesity and diabetes therapy: A Review. Journal of Oleo Science. 64,125 -132. (2015). 

Nanashima N, Horie K, Tomisawa T, Chiba M, Nakano M, Fujita T, Maeda H, Kitajima M, Takamagi S, Uchiyama D, Watanabe J, Nakamura T, Kato Y. Phytoestrogenic activity of blackcurrant (Ribes nigrum) anthocyanins is mediated through estrogen receptor alpha. Molecular nutrition & food research. 59(12):2419-2431. (2015). 

Islam M N, Maeda H, Kawasaki M. Effect of Calcium Concentration in Growth Medium on Oxalate Content and Evaluation of the Role of Guttation in the Regulation of Oxalate in Eddo. Plant Production Science. 18(4): 464-470. (2015). 

Maeda H, Yamazaki M, Katagata Y. Kuromoji (Lindera umbellata) essential oil inhibits LPS-induced inflammation in RAW 264.7 cells. Bioscience, biotechnology, and biochemistry. 77(3): 482-486. (2013). 

Maeda H, Saito S, Nakamura N, Maoka T. Paprika pigments attenuate obesity-induced inflammation in 3T3-L1 adipocytes. ISRN Inflammation. 2013:763758. (2013). 

Maeda H, Hosomi R, Chiba U, Fukunaga K. Chemical composition of salmon ovary outer membrane and its protein increases fecal mucins content in C57BL/6J and type 2 diabetic/obese KK-Ay mice. Foods. 2(3): 415-429. (2013). 

Maeda H. Anti-obesity and anti-diabetic activities of algae. Functional ingredients from algae for foods and nutraceuticals Chapter13, p453-472 Woodhead Publishing, ISBN: 978-085709-512-1 (2013). 

Maeda H, Yamazaki M, Katagata Y. Kuromoji (Lindera umbellata) essential oil-induced apoptosis and differentiation in human leukemia HL-60 cells. EXPERIMENTAL AND THERAPEUTIC MEDICINE. 3: 49-52. (2012). 

Maeda H, Abe M, Hosokawa M, Miyashita K, Katagata Y. Neoxanthin in Komatsuna improves lipid metabolism in adipocyte cells. Carotenoid Science. 17:51-52. (2012). 

Miyashita K, Maeda H, Nishikawa S, Tsukui T, TWidjaja-Adhi M A, Hosokawa M. Fucoxanthin as potential nutraceutical for obesity therapy : A Review. Carotenoid Science. 17:1-7. (2012). 

Maeda H, Hosokawa M, Sashima T, Murakami-Funayama K, Miyashita K. Anti-obesity and anti-diabetic effects of fucoxanthin on diet induced obesity conditions in murine model. Molecular Medicine Reports. 2:897- 902. (2009). 

Maeda H, Tsukui T, Sashima T, Hosokawa M, Miyashita K.Seaweed carotenoid, fucoxanthin, as a multi-functional nutrient. Asia Pac J Clin Nutr. 17(S1) , 196-199 (2008). 

Maeda H, Hosokawa M, Sashima T, Miyashita K. Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice. Journal of Agricultural and Food Chemistry. 55(19):7701-7706. (2007). 

Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K. Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin. Journal of oleo science. 56(12):615-621. (2007). 

Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, Miyashita K. Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. International Journal of Molecular Medicine. 18(1):147-152. (2006). 

Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K. Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues. Biochemical and Biophysical Research Communications. 332(2):392-397. (2005). 


Keyword : Lifestyle-related disease, Functional food, Obesity, Metabolic syndrome, Lipid chemistry, Phytochemical, Carotenoid
1.22.2019 update

Hayato Maeda